A New Minimum Order Lumped-Parameter Model of Circulatory System for Patients with Suffered Left and Right-Sided Heart Failure

Document Type : Research Article

Authors

1 Corresponding Author, E. Rouhani is with the Department of Electrical Engineering, Naghshejahan Institue, Esfahan, Iran (e.rouhani@aut.ac.ir)

2 S. Gharibzadeh is with the Department of Biomedical Engineering, Amirkabir University of Technology, Tehran, Iran (s.gharibzadeh@aut.ac.ir)

3 A.Abootalebi is with the Department of Electrical Engineering, Naghshejahan Institue, Esfahan, Iran (abootalebi_a@alumni.iut.ac.ir)

4 A. Karimian is with the Department of Electrical Engineering, Naghshejahan Institue, Esfahan, Iran (ali.karimian@pel.iaun.ac.ir)

5 F. Khalili Esfahani is with the Department of Electrical Engineering, Naghshejahan Institue, Esfahan, Iran (farzadkhalili2010@gmail.com)

Abstract

In this study a new minimum lumped electrical model of total circulatory system through numerical solutions to approximate the response of the human circulatory system was presented. Among five existent ventricular elastances as activity function of heart pumps, a more accurate model was chosen as well as the operation of baroreflex system to accommodate variations in heart rate and systemic vascular resistance of a native human circulatory system. The model with extracting the hemodynamic reaction of a patient with heart failure has the ability to study completely the influence of left heart failure on the right ventricle performance. The model can be used to analyze the variations of pressure-volume loop curve for normal hearts and dilated and hypertrophic heart failure patients at rest. The simulation results, in comparison with the clinical data, showed that the model could efficiently simulate the progressed states of heart failure with an acceptable accuracy and among all studied states of disease, hypertrophic LS and RSHF state caused to make critical conditions for the simulated patient.  

Keywords

References

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