Biomechanical Analysis of CNS Gray Matter in Tension and Compression

Mehdizadehi, Sina; Najarianii, Siamak; Farmanzadiii, Farhad; Khoshgoftariv, Mehdi

doi:10.22060/eej.2010.105

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Biomechanical Analysis of CNS Gray Matter in Tension and Compression

Article 6, Volume 42, Issue 1, Winter and Spring 2010, Page 45-50 PDF (301 K)

Document Type: Research Paper

DOI: 10.22060/eej.2010.105

Authors

Sina Mehdizadehi¹; Siamak Najarianii^* ²; Farhad Farmanzadiii³; Mehdi Khoshgoftariv⁴

¹S. Mehdizadeh is with the Faculty of Biomedical Engineering, Amirkabir University of Technology, Tehran, Iran (e-mail: s.mehdizadeh@aut.ac.ir).

²Corresponding Author, S. Najarian is with the Faculty of Biomedical Engineering, Amirkabir University of Technology, Tehran, Iran (e-mail: najarian@aut.ac.ir).

³F. Farmanzad is with the Department of Mechanical Engineering, Iran University of Science and Technology, Tehran, Iran (e-mail: f.farmanzad@sazeh.co.ir).

⁴M. Khoshgoftar is with the Faculty of Biomedical Engineering, Amirkabir University of Technology, Tehran, Iran (e-mail: p.khoshgoftar.eng@gmail.com).

Abstract

The purpose of this study is to survey cross section changes of the animal brain samples during the tension and compression tests and comparison of the experimental results for three animals: bovine, sheep, and rabbit. A linear elastic theory with considering the necking in tension and barreling in compression has been considered for brain tissue. Bridgman method for tension and cross section updating method (using a picture analyzing through a computer program to trace cross section changes during the test) for compression has been applied in order to consider necking and barreling. It is shown that the effect of cross section changes of the samples during the test is not negligible. Differences in the behavior of brain tissue of bovine, sheep, and rabbit in both compression and tension are discussed. Results are in good agreement with previous works in the literature.

Keywords

Biomechanics; Brain Tissue; Mechanical Behavior; Tension; Compression

References

[1] Farmanzad, F.; Najarian, S.; Eslami, M.; Seddighi, A.S.; “A novel model for biomechanical behavior of human brain in epidural hematoma injuries”, Bio-Med. Mater. and Eng., vol. 17 (2), p.p. 119-125, 2007.

[2] Pott, P.P.; Scharf, H.P.; Schwarz, M.L.R.; “Today’s state of the art surgical robotics”, J. of Comput. Aid. Surg., vol. 10 (2), p.p. 101-132, 2005.

[3] Taylor, Z.; Miller, K.; “Reassessment of brain elasticity for analysis of biomechanics of hydrocephalus”, J. of Biomech. Eng., vol. 37, p.p. 1263-1269, 2005.

[4] Walsh, E.K.; Schettini, A.; “Elastic behavior of brain tissue in vivo”, Am. J. Physiol., vol. 230, p.p. 1058-1062, 1976.

[5] Ommaya, A.K.; “Mechanical properties of tissues of the nervous system”, J. of Biomech., vol. 1, p.p. 127, 1968.

[6] Estes, M.S.; McElhaney, J.H.; “Response of brain tissue of compressive loading”, ASME Pub., 70-BHF-13, 4, 1970.

[7] Miller, K.; “Constitutive modeling of brain tissue: Experiment and theory”, J. of Biomech., vol. 30, p.p. 1115-1121, 1997.

[8] Miller, K.; Chinzei, K.; “Mechanical properties of brain tissue in tension”, J. of Biomech., vol 35, p.p. 483-490, 2002.

[9] Bilston, L.E.; Liu, Z.; Phan-Thien, N.; “Large strain behavior of brain tissue in shear: Some experimental data and differential constitutive model”, Biorheolog, vol. 38, p.p. 335-345, 2001.

[10] Brands, D.W.A.; Bovendeerd, P.H.M.; Peters, G.W.M.; Wismans, J.S.H.M.; “The large shear strain dynamic behavior of in-vitro porcine brain tissue and the silicone gel model material”, Proc. of the 44th Stapp Car Crash Conf., 2000-01-SC17, p.p. 249-260, 2000.

[11] Donnely, B.R.; Medige, J.; “Shear properties of human brain tissue”, J. of Biomech. Engin., vol. 119, p.p. 423-432, 1997.

[12] Prange, M.T.; Margulies, S.S.; “Regional, directional, and age-dependent properties of the brain undergoing large deformation”, J. of Biomech. Eng., vol. 124, p.p. 244-252, 2002.

[13] Miller, K.; “Constitutive model of brain tissue suitable for finite element analysis of surgical procedures”, J. of Biomech., vol. 32, p.p. 531-537, 1999.

[14] Franceschini, G.; Bigoni, D.; Regitni, P.; Holzapfel, G.A.; “Brain tissue deforms similarly to filled elastomers and follows consolidation theory”, J. of the Mech. and Physics of Solids, vol. 54: p.p. 2592–2620, 2006.

[15] Hashemi, J.; Bennettv, R.; “Materials Characterization: Tensile Test”, Mater. and Mech. Laborat., ME 3328, 2003.

[16] Ling, Y.; “Uniaxial True Stress-Strain after Necking”, AMP J. of Technolog., vol. 5,1996.

[17] Velardi, F.; Fraternali, F.; Angelillo, M.; “Anisotropic constitutive equations and experimental tensile behavior of brain tissue”, Biomech. Model Mechanbiol., vol. 5, p.p. 53–61, 2006.

[18] Mendis, K.K.; Stalnaker, R.L.; Advani, S.H.; “A constitutive relationship for large deformation finite element modelling of brain tissue”, J. of Biomech. Eng., vol. 117, p.p. 279–285, 1995.

[19] Khoshgoftar, M.; Najarian, S.; Farmanzad, F.; “A Biomechanical Composite Model to Determine Effective Elastic Moduli of the CNS Gray Matter”, Am. J. of Appl. Sci., vol. 4, p.p. 918-924, 2007.

[20] Miller, K.; Chinzei, K.; Orssengo, G.; Bednarz, P.; “Mechanical properties of brain tissue in vivo: experiment and computer simulation”, J. of Biomech., vol. 33, p.p. 1369-1376, 2000.

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